Transgenic Animals Applications And Examples

Applications Transgenic models for Alzheimer disease amyotrophic lateral sclerosis Huntington disease arthritis muscular dystrophy tumorigenesis hypertension neurodegenerative disorders endocrinological dysfunction coronary disease etc.

Transgenic animals applications and examples. A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. 2 Some transgenic animals are used as models for detecting diagnosing and treating different diseases. Species transgenic animals examples.

The term genetic engineering is used to describe the process Transgenic animal models of human disease can be useful for preclinical drug testing. The application of transgenic animals showed that within the next five to eight years genetically modified animals will play a significant and important role in the biomedical field in particular via the production of valuable pharmaceutical proteins and the supply of xenografts. Use of transgenic animals will provide solutions for drug research xenotransplantation clinical trials and will prove to be a new insight in drug development.

Examples of Transgenic Animals. The first genetically modified organism was a bacteria created in 1973 by Stanley N. One of them is the ability to engineer transgenic animals.

Sheep goats pigs cows rabbits rats mice fish insects parasites and even humans have previously been used in this modification process. Gene transfers have been successful in various fish such as common carp rainbow trout Atlantic salmon catfish goldfish zebra-fish etc. Transgenic expression is not only used to breed animals which have specific traits but also to breed animals that are lacking specific genes This technique is called as knockout or gene targeting.

Transgenic animals ie engineered to carry genes from other species have the potential to improve human welfare. For example we have transgenic models for diseases such as Alzheimers and cancer. Transgenic Animals Applications And Examples.

A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. Transgenic animals are used as tools in research and for the production of recombinant proteins The main applications of transgenic animals are described as followsStudying gene function. Foreign genes are inserted into the germ line of the animal so it can be transmitted to the progeny.